NLRP4 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP18739a
Background:
NALPs are cytoplasmic proteins that form a subfamilywithin the larger CATERPILLER protein family. Most short NALPs,such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain(PYD), followed by a NACHT domain, a NACHT-associated domain (NAD),and a C-terminal leucine-rich repeat (LRR) region. The long NALP,NALP1 (MIM 606636), also has a C-terminal extension containing afunction to find domain (FIIND) and a caspase recruitment domain(CARD). NALPs are implicated in the activation of proinflammatorycaspases (e.g., CASP1; MIM 147678) via their involvement inmultiprotein complexes called inflammasomes (Tschopp et al., 2003[PubMed 12563287]).
Other Names:
NACHT, LRR and PYD domains-containing protein 4, Cancer/testis antigen 58, CT58, PAAD and NACHT-containing protein 2, PAN2, PYRIN and NACHT-containing protein 2, PYRIN-containing APAF1-like protein 4, PYPAF4, Ribonuclease inhibitor 2, NLRP4, NALP4, PAN2, PYPAF4, RNH2
Gene Name: NLRP4 (HGNC:22943)
Gene ID: 147945
Primary Accession: Q96MN2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
NALPs are cytoplasmic proteins that form a subfamilywithin the larger CATERPILLER protein family. Most short NALPs,such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain(PYD), followed by a NACHT domain, a NACHT-associated domain (NAD),and a C-terminal leucine-rich repeat (LRR) region. The long NALP,NALP1 (MIM 606636), also has a C-terminal extension containing afunction to find domain (FIIND) and a caspase recruitment domain(CARD). NALPs are implicated in the activation of proinflammatorycaspases (e.g., CASP1; MIM 147678) via their involvement inmultiprotein complexes called inflammasomes (Tschopp et al., 2003[PubMed 12563287]).
Other Names:
NACHT, LRR and PYD domains-containing protein 4, Cancer/testis antigen 58, CT58, PAAD and NACHT-containing protein 2, PAN2, PYRIN and NACHT-containing protein 2, PYRIN-containing APAF1-like protein 4, PYPAF4, Ribonuclease inhibitor 2, NLRP4, NALP4, PAN2, PYPAF4, RNH2
Gene Name: NLRP4 (HGNC:22943)
Gene ID: 147945
Primary Accession: Q96MN2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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