NLRP7 Polyclonal Antibody

Background:
This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Cell Biology, Immunology

Synonyms:
CLR19.4, FLJ94610, HYDM, MGC126470, MGC126471, NACHT, leucine rich repeat and PYD containing 7, NACHT, LRR and PYD containing protein 7, NACHT, LRR and PYD domains containing protein 7, NACHT, LRR and PYD domains-containing protein 7, NALP7, NALP7, NLR family, pyrin domain containing 7, NLRP7, NOD12, Nucleotide-binding oligomerization domain protein 12, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7, PAN7, PYPAF3, PYRIN-containing APAF1-like protein 3

Immunogen: Synthetic peptide of human NLRP7

Swissprot: Q8WX94
Gene Accession: NP_001120727

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-50641/sc-50642/sc-50643/sc-99001