NM23-H1 Polyclonal Antibody

Background:
NME/NM23 nucleoside diphosphate kinase 1(NME1) Homo sapiens This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008],

Alternative Names:
NME1, NDPKA, NM23, Nucleoside diphosphate kinase A, NDK A, NDP kinase A, Granzyme A-activated DNase, GAAD, Metastasis inhibition factor nm23, Tumor metastatic process-associated protein, nm23-H1

Immunogen: The antiserum was produced against synthesized peptide derived from human NM23-H1. AA range:3-52

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 23

GeneID: NME1

Storage: -20°C/1 year

NOTE: For Research Use Only