NMB polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60195
Background:
NMB (neuromedin-B) is a 121 amino acid secreted protein that belongs to the bombesin/neuromedin-B/ranatensin family and exists as two alternatively spliced isoforms. Acting in a manner similar to that of bombesin, NMB stimulates smooth muscle contraction. The gene that encodes NMB consists of about 3,443 bases and maps to human chromosome 15q25. Housing approximately 106 million base pairs and encoding more than 700 genes, chromosome 15 makes up about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.
Alternative Name:
Neuromedin B, Neuromedin-B-32, Neuromedin-B
Application Dilution: WB: 1:500~1:1000
Specificity: NMB polyclonal antibody detects endogenous levels of NMB protein.
Immunogen:
A synthetic peptide corresponding to residues in Human NMB.
MW: ~ 13 kDa
Swis Prot.: P08949
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
NMB (neuromedin-B) is a 121 amino acid secreted protein that belongs to the bombesin/neuromedin-B/ranatensin family and exists as two alternatively spliced isoforms. Acting in a manner similar to that of bombesin, NMB stimulates smooth muscle contraction. The gene that encodes NMB consists of about 3,443 bases and maps to human chromosome 15q25. Housing approximately 106 million base pairs and encoding more than 700 genes, chromosome 15 makes up about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.
Alternative Name:
Neuromedin B, Neuromedin-B-32, Neuromedin-B
Application Dilution: WB: 1:500~1:1000
Specificity: NMB polyclonal antibody detects endogenous levels of NMB protein.
Immunogen:
A synthetic peptide corresponding to residues in Human NMB.
MW: ~ 13 kDa
Swis Prot.: P08949
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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