NMD3 polyclonal (C-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP1948b
Catalog Number: AC-AP1948b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB9708
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB9708
Applications: WB
Datasheet
Request Information
Background:
It has been suggested that NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit but is not a ribosomal protein. A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. The NMD3 protein sequence does not contain readily recognizable motifs of known function. However, NMD3 orthologues display an amino-terminal domain containing four repeats of Cx2C, reminiscent of zinc-binding proteins, implicated in nucleic acid binding or protein oligomerization.
Other Names:
60S ribosomal export protein NMD3, hNMD3, NMD3
Target/Specificity:
This NMD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-440 amino acids from the C-terminal region of human NMD3.
Antigen Region:
410-440
Antigen Type: Synthetic Peptide
Gene Name: NMD3
Gene ID: 51068
Primary Accession: Q96D46
NCBI Accession: NP_057022.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
It has been suggested that NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit but is not a ribosomal protein. A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. The NMD3 protein sequence does not contain readily recognizable motifs of known function. However, NMD3 orthologues display an amino-terminal domain containing four repeats of Cx2C, reminiscent of zinc-binding proteins, implicated in nucleic acid binding or protein oligomerization.
Other Names:
60S ribosomal export protein NMD3, hNMD3, NMD3
Target/Specificity:
This NMD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-440 amino acids from the C-terminal region of human NMD3.
Antigen Region:
410-440
Antigen Type: Synthetic Peptide
Gene Name: NMD3
Gene ID: 51068
Primary Accession: Q96D46
NCBI Accession: NP_057022.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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