NMDAε4 (P706) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS3868
Background:
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors exhibit slow kinetsis of Ca2+ ions and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: ε 1, 2, 3, 4 and one ζ subunit. The ζ subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.
Alternative Name:
Glutamate receptor ionotropic, NMDA 2D, GluN2D, EB11, Glutamate [NMDA] receptor subunit epsilon-4, N-methyl D-aspartate receptor subtype 2D, Short name=NMDAR2D, Short name=NR2D, GRIN2D, GluN2D, NMDAR2D
Application Dilution: IHC: 1:50~1:200
Specificity: NMDAε4 (P706) polyclonal antibody detects endogenous levels of NMDAε4 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 681-730 of Human NMDAε4.
MW: ~ 170 kDa
Swis Prot.: O15399
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors exhibit slow kinetsis of Ca2+ ions and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: ε 1, 2, 3, 4 and one ζ subunit. The ζ subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.
Alternative Name:
Glutamate receptor ionotropic, NMDA 2D, GluN2D, EB11, Glutamate [NMDA] receptor subunit epsilon-4, N-methyl D-aspartate receptor subtype 2D, Short name=NMDAR2D, Short name=NR2D, GRIN2D, GluN2D, NMDAR2D
Application Dilution: IHC: 1:50~1:200
Specificity: NMDAε4 (P706) polyclonal antibody detects endogenous levels of NMDAε4 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 681-730 of Human NMDAε4.
MW: ~ 170 kDa
Swis Prot.: O15399
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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