NMDAR1 polyclonal, anti-human, mouse, rat

Background:
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.

Alternative Name:
GluN1, NMD-R1, GluN1, Glutamate [NMDA] receptor subunit zeta-1, Glutamate receptor ionotropic N methyl D aspartate 1, Glutamate receptor ionotropic, N-methyl-D aspartate, subunit 1, glutamate receptor ionotropic, NMDA 1, Grin1, MRD8, N methyl D aspartate receptor, N methyl D aspartate receptor channel subunit zeta 1, N methyl D aspartate receptor subunit NR1, N-methyl-D-aspartate receptor subunit NR1, NMD-R1, NMDA 1, NMDA R1, NMDA receptor 1, NMDA1, NMDAR, NMDZ1, NR1,

Application Dilution:
WB:1:500-1:2,000
ICC:1:100-1:500
IHC:1:50-1:200
FC:1:50-1:100

Specificity: NMDAR1 polyclonal antibody detects endogenous levels of NMDAR1 protein.

Immunogen:
recombinant protein

MW: 105 kDa

Swiss-Prot: Q05586(Human) P35438(Mouse) P35439(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.