NME1 antibody (clone 1D7), anti-human
€435.00
In stock
SKU
AC-AT3065a
Catalog Number: AC-AT3065a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF, IP, E
Request Information AC-AT3065a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF, IP, E
Request Information AC-AT3065a">Request Information
Background:
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Other Names:
Nucleoside diphosphate kinase A, NDK A, NDP kinase A, Granzyme A-activated DNase, GAAD, Metastasis inhibition factor nm23, NM23-H1, Tumor metastatic process-associated protein, NME1, NDPKA, NM23
Antigen Type:
Recombinant Protein
Gene Name: NME1
Gene ID: 4830
NCBI Accession: NP_000260.1;NP_937818.1
Primary Accession: P15531
Other Accession: NM_000269
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Other Names:
Nucleoside diphosphate kinase A, NDK A, NDP kinase A, Granzyme A-activated DNase, GAAD, Metastasis inhibition factor nm23, NM23-H1, Tumor metastatic process-associated protein, NME1, NDPKA, NM23
Antigen Type:
Recombinant Protein
Gene Name: NME1
Gene ID: 4830
NCBI Accession: NP_000260.1;NP_937818.1
Primary Accession: P15531
Other Accession: NM_000269
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review