NME1 Polyclonal Antibody

Background:
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
AWD, AWD, drosophila, homolog of, GAAD, Granzyme A activated DNase, Granzyme A-activated DNase, GZMA activated DNase, Metastasis inhibition factor NM23, NB, NBS, NDK A, NDKA, NDKA, NDP kinase A, NDPK-A, NDPKA, NM23, NM23 long variant, included, nm23-H1, NM23-M1, NM23H1B, included, NME/NM23 nucleoside diphosphate kinase 1, Nme1, NME1-NME2 spliced read-through transcript, included, Non-metastatic cells 1, protein (NM23A) expressed in, Nonmetastatic cells 1, protein expressed in, Nonmetastatic protein 23, Nonmetastatic protein 23, homolog 1, Nucleoside diphosphate kinase A, Tumor metastatic process-associated protein

Immunogen: Recombinant protein of human NME1

Swissprot: P15531
Gene Accession: BC000293

Calculated MW: 17 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-14787/sc-17586/sc-343/sc-28829