NMT1 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP2519a
Background:
N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases.
Other Names:
Glycylpeptide N-tetradecanoyltransferase 1, Myristoyl-CoA:protein N-myristoyltransferase 1, NMT 1, Type I N-myristoyltransferase, Peptide N-myristoyltransferase 1, NMT1, NMT
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2519a was selected from the N-term region of human NMT1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NMT1 {ECO:0000303|PubMed:9506952, ECO:0000312|HGNC:HGNC:7857}
Gene ID: 4836
Primary Accession: P30419
Other Accession: NP_066565
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases.
Other Names:
Glycylpeptide N-tetradecanoyltransferase 1, Myristoyl-CoA:protein N-myristoyltransferase 1, NMT 1, Type I N-myristoyltransferase, Peptide N-myristoyltransferase 1, NMT1, NMT
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2519a was selected from the N-term region of human NMT1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NMT1 {ECO:0000303|PubMed:9506952, ECO:0000312|HGNC:HGNC:7857}
Gene ID: 4836
Primary Accession: P30419
Other Accession: NP_066565
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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