nNOS (neuronal) NOS1 monoclonal, anti-human, mouse, rat

nNOS (neuronal) NOS1 monoclonal, anti-human, mouse, rat

€455.00
In stock
SKU
AC-ABO14206
Catalog Number: AC-ABO14206
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC, IP, FC
Datasheet
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Description: Anti-nNOS (neuronal) NOS1 Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Protein Function:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.

Other Names: Nitric oxide synthase 1 {ECO:0000312|HGNC:HGNC:7872}, 1.14.13.39, Constitutive NOS, NC-NOS, NOS type I, Neuronal NOS, N-NOS, nNOS, Nitric oxide synthase, brain, bNOS, Peptidyl-cysteine S-nitrosylase NOS1, NOS1 (HGNC:7872)

Clone Name(s):
Clone: CEI-14

Subcellular Localization: Cell membrane, sarcolemma; Peripheral membrane protein. Cell projection, dendritic spine. In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines (By similarity)..

Tissue Specificity: Isoform 1 is ubiquitously expressed: detected in skeletal muscle and brain, also in testis, lung and kidney, and at low levels in heart, adrenal gland and retina. Not detected in the platelets. Isoform 3 is expressed only in testis. Isoform 4 is detected in testis, skeletal muscle, lung, and kidney, at low levels in the brain, but not in the heart and adrenal gland.

Gene ID: 4842

Immunogen: A synthesized peptide derived from human nNOS (neuronal)

Calculated MW: 160970

Purification: Affinity-chromatography

Format: Liquid

Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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