NOD4 polyclonal, anti-human, mouse
€484.00
In stock
SKU
254341
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction
Description:
NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-kappaB and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.
Alternate Names: NOD4, NLR family CARD domain containing 5, NLRC5, Caterpiller protein 16.1, NOD27
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_115582
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human NOD4.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-kappaB and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.
Alternate Names: NOD4, NLR family CARD domain containing 5, NLRC5, Caterpiller protein 16.1, NOD27
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_115582
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human NOD4.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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