Nodal Polyclonal Antibody

Nodal Polyclonal Antibody

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In stock
SKU
ELK-ES8406
Catalog Number: ELK-ES8406
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
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Background:
nodal growth differentiation factor(NODAL) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis. [provided by RefSeq, Aug 2016],

Alternative Names:
NODAL, Nodal homolog

Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human NODAL. AA range:294-343

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 40

GeneID: NODAL

Storage: -20°C/1 year

NOTE: For Research Use Only
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