NOGO polyclonal, anti-human, mouse, rat

Protein Family: Receptors and Channels

Pathway and Disease: Cell Growth and Death, Nervous and Sensory Systems, Neurodegenerative Disorders, Signaling Molecules and Interaction

Description:
Reticulon-4 (neuroendocrine-specific protein, NOGO) is a reticulon protein expressed by the axonal oligodendrocytes. NOGO contributes to the axonal growth inhibitory action of the central myelin in growth cone collapse and neurite outgrowth. Antibody and inhibitory studies have implicated a regenerative role for NOGO in the adult CNS.

Alternate Names: Reticulon-4, Neurite outgrowth inhibitor, Nogo protein, Foocen, Neuroendocrine-specific protein, NSP, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5, RTN4, NOGO

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500

Accession No.: Q9NQC3

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NOGO.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.