Nogo polyclonal, anti-human, mouse, rat

Protein Family: Cytokines

Pathway and Disease: Signaling Molecules and Interaction, Cell Growth and Death, Nervous and Sensory Systems

Description:
Neurite outgrowth inhibitor (Nogo) is a developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Nogo regulates neurite fasciculation, branching and extension in the developing nervous system. Nogo is involved in the down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS.

Alternate Names: Nogo protein, Reticulon-4, Neurite outgrowth inhibitor, Foocen, Neuroendocrine-specific protein, NSP, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5, RTN4, KIAA0886, NOGO

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; ICC: 1:100-1:500

Accession No.: Q9NQC3

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Nogo.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.