NOL10 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61668
Background:
Nucleolar protein 10：By immunoprecipitation of human AATF we discovered that AATF forms a salt-stable protein complex together with neuroguidin (NGDN) and NOL10, and demonstrate that the AATF-NGDN-NOL10 (ANN) complex functions in ribosome biogenesis. All three ANN complex members localize to nucleoli and display a mutual dependence with respect to protein stability. Mapping of protein-protein interaction domains revealed the importance of both the evolutionary conserved WD40 repeats in NOL10 and the UTP3/SAS10 domain in NGDN for complex formation.
Alternative Name:
Nucleolar protein 10, NOL10
Application Dilution: WB: 1:500~1:1000
Specificity: NOL10 polyclonal antibody detects endogenous levels of NOL10 protein.
Immunogen:
Synthetic peptide, corresponding Human NOL10.
MW: ~ 80 kDa
Swis Prot.: Q9BSC4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Nucleolar protein 10：By immunoprecipitation of human AATF we discovered that AATF forms a salt-stable protein complex together with neuroguidin (NGDN) and NOL10, and demonstrate that the AATF-NGDN-NOL10 (ANN) complex functions in ribosome biogenesis. All three ANN complex members localize to nucleoli and display a mutual dependence with respect to protein stability. Mapping of protein-protein interaction domains revealed the importance of both the evolutionary conserved WD40 repeats in NOL10 and the UTP3/SAS10 domain in NGDN for complex formation.
Alternative Name:
Nucleolar protein 10, NOL10
Application Dilution: WB: 1:500~1:1000
Specificity: NOL10 polyclonal antibody detects endogenous levels of NOL10 protein.
Immunogen:
Synthetic peptide, corresponding Human NOL10.
MW: ~ 80 kDa
Swis Prot.: Q9BSC4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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