NOL3 Polyclonal Antibody

Background:
This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.

Research Area: Cell Biology

Synonyms:
Apoptosis repressor with CARD, ARC, Muscle enriched cytoplasmic protein, Muscle-enriched cytoplasmic protein, MYC, MYP, Nol3, NOL3, NOP, Nop30, Nucleolar protein 3 (apoptosis repressor with CARD domain), Nucleolar protein 3, Nucleolar protein of 30 kDa

Immunogen: Recombinant protein of human NOL3

Swissprot: O60936
Gene Accession: BC012798

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-19495/sc-19496/sc-11435