NOM1 polyclonal, anti-human, rat
€305.00
In stock
SKU
BS61227
Background:
NOM1 (nucleolar protein with MIF4G domain 1), also known as SGD1, is an 860 amino acid protein that localizes to the nucleolus, where it plays a role in targeting PP1. A member of the CWC22 family, NOM1 is expressed in skeletal muscle and heart, and contains one MI domain and a MIF4G domain. The MIF4G typically functions in protein translation and may act as a binding site for members of the eIF4A family. As such, NOM1 is thought to interact with eIF4AI, eIF4AII and eIF4AIII. The gene encoding NOM1 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Alternative Name:
Nucleolar MIF4G domain-containing protein 1, SGD1 homolog, NOM1, C7orf3
Application Dilution: WB: 1:500~1:1000
Specificity: NOM1 polyclonal antibody detects endogenous levels of NOM1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human NOM1.
MW: ~ 96 kDa
Swis Prot.: Q5C9Z4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
NOM1 (nucleolar protein with MIF4G domain 1), also known as SGD1, is an 860 amino acid protein that localizes to the nucleolus, where it plays a role in targeting PP1. A member of the CWC22 family, NOM1 is expressed in skeletal muscle and heart, and contains one MI domain and a MIF4G domain. The MIF4G typically functions in protein translation and may act as a binding site for members of the eIF4A family. As such, NOM1 is thought to interact with eIF4AI, eIF4AII and eIF4AIII. The gene encoding NOM1 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Alternative Name:
Nucleolar MIF4G domain-containing protein 1, SGD1 homolog, NOM1, C7orf3
Application Dilution: WB: 1:500~1:1000
Specificity: NOM1 polyclonal antibody detects endogenous levels of NOM1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human NOM1.
MW: ~ 96 kDa
Swis Prot.: Q5C9Z4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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