NONO polyclonal, anti-human antibody
€275.00
In stock
SKU
AC-ABV10572-100
Catalog Number: AC-ABV10572-100
Size: 100 µl
Host: Rabbit IgG
Applications: WB, IP
Datasheet
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Size: 100 µl
Host: Rabbit IgG
Applications: WB, IP
Datasheet
Request Information
Background:
Non-POU-domain-containing octamer binding protein (NONO) is a member of the DBHS (drosophila behavior, human splicing) domain-containing family and is an RNA- and DNA- binding protein. NONO and other DBHS domain-containing proteins are multifunctional and are reported to be involved in transcriptional regulation, mRNA processing, and DNA non-homologous end joining (NHEJ). NONO functions as a coregulator of the androgen receptor (AR) and also regulates cAMP transcriptional activity by interacting with gene promoter elements. NONO is also involved in pre-mRNA splicing through an interaction with U5 snRNA and can stimulate DNA nonhomologous end joining (NHEJ) through the interaction with ku70/G22p and ku80/XRCC5 dimers.
Other Names:
NONO, Non-POU Domain Containing, Octamer-binding, NRB54, P54NRB, Nuclear RNA-binding protein, 54kD, NMT54
Primary Accession: Q15233
Other Accession: NP_031389.3
Gene Name: NONO
Gene ID: 4841
Non-POU-domain-containing octamer binding protein (NONO) is a member of the DBHS (drosophila behavior, human splicing) domain-containing family and is an RNA- and DNA- binding protein. NONO and other DBHS domain-containing proteins are multifunctional and are reported to be involved in transcriptional regulation, mRNA processing, and DNA non-homologous end joining (NHEJ). NONO functions as a coregulator of the androgen receptor (AR) and also regulates cAMP transcriptional activity by interacting with gene promoter elements. NONO is also involved in pre-mRNA splicing through an interaction with U5 snRNA and can stimulate DNA nonhomologous end joining (NHEJ) through the interaction with ku70/G22p and ku80/XRCC5 dimers.
Other Names:
NONO, Non-POU Domain Containing, Octamer-binding, NRB54, P54NRB, Nuclear RNA-binding protein, 54kD, NMT54
Primary Accession: Q15233
Other Accession: NP_031389.3
Gene Name: NONO
Gene ID: 4841
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