NOR-1 (Y419) polyclonal, anti-human, mouse, rat

Background:
Nur77 (also designated NGFI-B), Nurr1 (Nur-related factor 1) and NOR-1 (neuron-derived orphan receptor-1) constitute the NGFI-B subfamily within the nuclear receptor superfamily.The human NOR-1 gene maps to chromosome 9q and encodes a protein which is expressed in heart, skeletal muscle, thymus and spleen as well as in brain, where it is developmentally regulated. Therefore, NOR-1 may be involved in regulating neural differentiation. The NOR-1 gene also undergoes chromosomal translocation with the EWS gene to produce a protein thought to affect pre-mRNA splicing.

Alternative Name:
Nuclear receptor subfamily 4 group A member 3, Mitogen-induced nuclear orphan receptor, Neuron-derived orphan receptor 1, Nuclear hormone receptor NOR-1, NR4A3, CHN, CSMF, MINOR, NOR1, TEC

Application Dilution:
WB: 1:500~1:1000

Specificity: NOR-1 (Y419) polyclonal antibody detects endogenous levels of NOR-1 protein.

Immunogen:
Synthetic peptide, corresponding to amino acids 389-435 of Human NOR-1.

MW: ~ 68 kDa

Swiss-Prot: Q92570

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.