Norepinephrine Transporter (clone ), anti-mouse, rat
€510.00
In stock
SKU
253181
Protein Family: Transporters
Pathway and Disease: Signaling Molecules and Interaction, Signal Transduction, Nervous and Sensory Systems, Neurodegenerative Disorders
Description:
Norepinephrine Transporter [NET] (or noradrenaline transporter (NAT)) is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression. Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (Serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD.
Alternate Names: Sodium-dependent noradrenaline transporter, Norepinephrine transporter, NET Solute carrier family 6 member 2
Application Notes: E: 1:500-1:1,000; WB: 1:2,000
Accession No.: O55192
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within mouse norepinephrine transporter.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction, Signal Transduction, Nervous and Sensory Systems, Neurodegenerative Disorders
Description:
Norepinephrine Transporter [NET] (or noradrenaline transporter (NAT)) is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression. Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (Serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD.
Alternate Names: Sodium-dependent noradrenaline transporter, Norepinephrine transporter, NET Solute carrier family 6 member 2
Application Notes: E: 1:500-1:1,000; WB: 1:2,000
Accession No.: O55192
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within mouse norepinephrine transporter.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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