NOS1 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.

Synonyms: IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS

Cellular Location: Cell membrane Cell projection Peripheral membrane protein dendritic spine sarcolemma

Immunogen:
Recombinant Protein of human NOS1

Gene Symbol: NOS1

Gene ID: 4842

Swiss prot: P29475

Calculated MW: 161kDa

Recommended dilution:
WB 1:500-2000, IF 1:20-50,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.