NOSTN Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission| inflammatory response| and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production| endothelial NO synthase (ENOS; MIM 163729)| and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures| thereby attenuating ENOS-dependent NO production.

Research Area: Epigenetics and nuclear signaling

Synonyms: NOSTN

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year