NOX4 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

Synonyms: KOX, KOX-1, RENOX

Cellular Location: cytoplasm Nucleus

Immunogen:
Recombinant protein of human NOX4

Gene Symbol: NOX4

Gene ID: 50507

Swiss prot: Q9NPH5

Calculated MW: 67/58/32/63/6kDa

Recommended dilution:
IHC 1:25-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.