Noxa monoclonal, anti-human, mouse
€455.00
In stock
SKU
AC-ABO13537
Catalog Number: AC-ABO13537
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB
Datasheet
Request Information
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB
Datasheet
Request Information
Description: Anti-Noxa Rabbit Monoclonal Antibody . Tested in WB application. This antibody reacts with Human, Mouse.
Protein Function:
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1..
Other Names: Phorbol-12-myristate-13-acetate-induced protein 1, PMA-induced protein 1, Immediate-early-response protein APR, Protein Noxa, PMAIP1, NOXA
Clone Name(s):
Clone: AAFB-16
Subcellular Localization: Mitochondrion.
Tissue Specificity: Highly expressed in adult T-cell leukemia cell line.
Gene ID: 5366
Immunogen: A synthesized peptide derived from human Noxa
Calculated MW: 6030
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Function:
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1..
Other Names: Phorbol-12-myristate-13-acetate-induced protein 1, PMA-induced protein 1, Immediate-early-response protein APR, Protein Noxa, PMAIP1, NOXA
Clone Name(s):
Clone: AAFB-16
Subcellular Localization: Mitochondrion.
Tissue Specificity: Highly expressed in adult T-cell leukemia cell line.
Gene ID: 5366
Immunogen: A synthesized peptide derived from human Noxa
Calculated MW: 6030
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
| Is Featured? | No |
|---|
Write Your Own Review