NOXA2 / P67phox Polyclonal Antibody

Background:
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Cancer, Metabolism, Immunology

Synonyms:
NCF2, NCF-2, NOXA2, P67-PHOX, P67PHOX

Immunogen: Recombinant fusion protein of human NOXA2 / P67phox (NP_000424.2).

Swissprot: P19878
Gene ID: 4688

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.