NPAS2 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5828
Background:
Members of the basic helix-loop-helix-PER-ARNT-SIM (bHLH-PAS) family are transcription factors that contain a bHLH DNA binding domain located amino-terminal to a PAS domain. Neuronal PAS domain protein 2 (NPAS2, also designated PAS 4/MOP4) is a member of the bHLH-PAS family and the PAS superfamily. NPAS2, which maps to chromosome 2p11.2-2q13, is expressed primarily in the neurons during the first week of postnatal development. The pattern of NPAS2 expression temporally matches the development of learning and memory, and spatially matches the frontal association/limbic forebrain pathway. NPAS2 may serve a regulatory role in the development and maintenance of long-term memory, and may be required for the processing of complex sensory information. NPAS2 and MOP3 form a transcriptionally active heterodimer which binds to a CACGTGA-containing DNA element and drives transcription from a linked luciferase reporter gene.
Alternative Name:
Neuronal PAS domain-containing protein 2, Neuronal PAS2, Basic-helix-loop-helix-PAS protein MOP4, Class E basic helix-loop-helix protein 9, bHLHe9, Member of PAS protein 4, PAS domain-containing protein 4, NPAS2, BHLHE9, MOP4, PASD4
Application Dilution: WB: 1:500~1:1000
Specificity: NPAS2 polyclonal antibody detects endogenous levels of NPAS2 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 403-448 of Human NPAS2.
MW: ~ 91 kDa
Swis Prot.: Q99743
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Members of the basic helix-loop-helix-PER-ARNT-SIM (bHLH-PAS) family are transcription factors that contain a bHLH DNA binding domain located amino-terminal to a PAS domain. Neuronal PAS domain protein 2 (NPAS2, also designated PAS 4/MOP4) is a member of the bHLH-PAS family and the PAS superfamily. NPAS2, which maps to chromosome 2p11.2-2q13, is expressed primarily in the neurons during the first week of postnatal development. The pattern of NPAS2 expression temporally matches the development of learning and memory, and spatially matches the frontal association/limbic forebrain pathway. NPAS2 may serve a regulatory role in the development and maintenance of long-term memory, and may be required for the processing of complex sensory information. NPAS2 and MOP3 form a transcriptionally active heterodimer which binds to a CACGTGA-containing DNA element and drives transcription from a linked luciferase reporter gene.
Alternative Name:
Neuronal PAS domain-containing protein 2, Neuronal PAS2, Basic-helix-loop-helix-PAS protein MOP4, Class E basic helix-loop-helix protein 9, bHLHe9, Member of PAS protein 4, PAS domain-containing protein 4, NPAS2, BHLHE9, MOP4, PASD4
Application Dilution: WB: 1:500~1:1000
Specificity: NPAS2 polyclonal antibody detects endogenous levels of NPAS2 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 403-448 of Human NPAS2.
MW: ~ 91 kDa
Swis Prot.: Q99743
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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