NPHP3 Rabbit polyclonal antibody, anti-human, mouse

Background:
This gene encodes a protein containing a coiled-coil (CC) domain| a tubulin-tyrosine ligase (TTL) domain| and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin| it is required for normal ciliary development| and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3| and also with renal-hepatic-pancreatic dysplasia| and Meckel syndrome type 7. Naturally occurring read-through transcripts exist between this gene and the downstream ACAD11 (acyl-CoA dehydrogenase family| member 11) gene.

Research Area: Signal transduction

Synonyms: NPHP3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year