NPM polyclonal, anti-human, mouse, rat antibody
€295.00
In stock
SKU
AC-ABV10310-100
Catalog Number: AC-ABV10310-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC
Datasheet
Request Information
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC
Datasheet
Request Information
Background:
NPM (Nucleophosmin) is an abundant phosphoprotein primarily found in nucleoli. It has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication and molecular chaperoning activities. The NPM gene is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM portion contributes to transformation by providing a dimerization domain, which results in activation of the fused kinase.
Other Names:
B23 , numatrin , NO38 , MGC104254 , Nucleophosmin , NPM1, Nucleolar phosphoprotein B23, Nucleolar protein NO38
Primary Accession: P06748
Gene Name: NPM1
Gene ID: 4869
Concentration (mg/ml): 0.5 mg/ml
NPM (Nucleophosmin) is an abundant phosphoprotein primarily found in nucleoli. It has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication and molecular chaperoning activities. The NPM gene is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM portion contributes to transformation by providing a dimerization domain, which results in activation of the fused kinase.
Other Names:
B23 , numatrin , NO38 , MGC104254 , Nucleophosmin , NPM1, Nucleolar phosphoprotein B23, Nucleolar protein NO38
Primary Accession: P06748
Gene Name: NPM1
Gene ID: 4869
Concentration (mg/ml): 0.5 mg/ml
| Is Featured? | No |
|---|
Write Your Own Review