NPM1 (clone 2D9-C3-E5), anti-human, mouse

Background:
This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

Synonyms: B23, NPM

Cellular Location: Cytoplasm Nucleus centrosome cytoskeleton microtubule organizing center nucleolus nucleoplasm

Immunogen:
Purified recombinant full length of human NPM1 protein expressed in E.coli.

Gene Symbol: NPM1

Gene ID: 4869

Swiss prot: P06748

Calculated MW: 38kDa

Recommended dilution:
WB 1:1000, ICC 1:200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.