NPM1 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP2834b
Catalog Number: AC-AP2834b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB17470
Applications: IF, WB, IHC-P, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB17470
Applications: IF, WB, IHC-P, FC
Datasheet
Request Information
Background:
NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF. NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia.
Other Names:
Nucleophosmin, NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, NPM1, NPM
Target/Specificity:
This NPM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human NPM1.
Antigen Region:
198-226
Antigen Type: Synthetic Peptide
Gene Name: NPM1
Gene ID: 4869
Primary Accession: P06748
NCBI Accession: NP_001032827.1;NP_002511.1;NP_954654.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF. NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia.
Other Names:
Nucleophosmin, NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, NPM1, NPM
Target/Specificity:
This NPM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human NPM1.
Antigen Region:
198-226
Antigen Type: Synthetic Peptide
Gene Name: NPM1
Gene ID: 4869
Primary Accession: P06748
NCBI Accession: NP_001032827.1;NP_002511.1;NP_954654.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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