NPPA polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1.

Synonyms: ANF, ANP, ATFB6, ATRST2, CDD, CDD-ANF, CDP, PND

Cellular Location: Secreted

Immunogen:
Recombinant protein of human NPPA

Gene Symbol: NPPA

Gene ID: 4878

Swiss prot: P01160

Calculated MW: 17kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:10-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.