NPPB Polyclonal Antibody

Background:
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.

Research Area: Cancer, Cardiovascular, Neuroscience

Synonyms:
ANFB, BNP, BNP(1-32), BNP(5-29), BNP-32, Brain type natriuretic peptide, Gamma brain natriuretic peptide, Gamma-brain natriuretic peptide, Natriuretic peptide precursor B, nppb, NT proBNP

Immunogen: Recombinant protein of human NPPB

Swissprot: P16860
Gene Accession: BC025785

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-18814/sc-18813/sc-20159