NPPC polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60381
Background:
Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP) . ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control . ANP, BNP, and CNP are highly homologous within the 17-residue ring structure formed by an intramolecular disulfide linkage . The genes which encode for ANP and BNP map to human chromosome 1p36.2 . The gene which encodes for CNP maps to human chromosome 2q24-qter .
Alternative Name:
C-type natriuretic peptide, Cleaved into the following 3 chains:CNP-22, CNP-29, CNP-53, NPPC, CNP2
Application Dilution: WB: 1:500~1:1000
Specificity: NPPC polyclonal antibody detects endogenous levels of NPPC protein.
Immunogen:
A synthetic peptide corresponding to residues in Human NPPC.
MW: ~ 7 kDa
Swis Prot.: P23582
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP) . ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control . ANP, BNP, and CNP are highly homologous within the 17-residue ring structure formed by an intramolecular disulfide linkage . The genes which encode for ANP and BNP map to human chromosome 1p36.2 . The gene which encodes for CNP maps to human chromosome 2q24-qter .
Alternative Name:
C-type natriuretic peptide, Cleaved into the following 3 chains:CNP-22, CNP-29, CNP-53, NPPC, CNP2
Application Dilution: WB: 1:500~1:1000
Specificity: NPPC polyclonal antibody detects endogenous levels of NPPC protein.
Immunogen:
A synthetic peptide corresponding to residues in Human NPPC.
MW: ~ 7 kDa
Swis Prot.: P23582
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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