NPR2 polyclonal, anti-human, mouse, rat

Background:
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity.

Synonyms: AMDM, ANPb, ECDM, NPRB, ANPRB, GUC2B, NPRBi, GUCY2B

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human NPR2

Gene Symbol: NPR2

Gene ID: 4882

Swiss prot: P20594

Calculated MW: 117kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.