NPR2 Polyclonal Antibody

Background:
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity.

Research Area: Cancer, Cardiovascular, Neuroscience, Signal Transduction

Synonyms:
AMDM, ANP-B, ANPB, ANPR-B, ANPRB, ANPRB, Atrial natriuretic peptide B type receptor, Atrial natriuretic peptide receptor 2, Atrial natriuretic peptide receptor type B, Atrionatriuretic peptide receptor B, GC-B, GCB, Guanylate cyclase B, GUC 2B, GUC2B, GUCY2B, Natriuretic peptide receptor B, Natriuretic peptide receptor B/guanylate cyclase B, NPR-B, Npr2, NPRB, NPRBi

Immunogen: Synthetic peptide of human NPR2

Swissprot: P20594
Gene Accession: NP_003986

Calculated MW: 117 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.9 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-34424/sc-34423/sc-34421/sc-34422/sc-16869/sc-16870/sc-25486