NPRL3 Blocking Peptide (N-Term)
€363.00
In stock
SKU
AC-BP21877a
Background:
As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC- containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.
Other Names:
Nitrogen permease regulator 3-like protein, -14 gene protein, Alpha-globin regulatory element-containing gene protein, Protein CGTHBA, NPRL3, C16orf35, CGTHBA, MARE
Target/Specificity:
The synthetic peptide sequence is selected from aa 106-117 of HUMAN NPRL3
Gene Name: NPRL3 {ECO:0000303|PubMed:26505888, ECO:0000312|HGNC:HGNC:14124}
Gene ID: 8131
Primary Accession: Q12980
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC- containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.
Other Names:
Nitrogen permease regulator 3-like protein, -14 gene protein, Alpha-globin regulatory element-containing gene protein, Protein CGTHBA, NPRL3, C16orf35, CGTHBA, MARE
Target/Specificity:
The synthetic peptide sequence is selected from aa 106-117 of HUMAN NPRL3
Gene Name: NPRL3 {ECO:0000303|PubMed:26505888, ECO:0000312|HGNC:HGNC:14124}
Gene ID: 8131
Primary Accession: Q12980
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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