NPTX2 polyclonal, anti-human
€388.00
In stock
SKU
BS71484
Background:
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
Alternative Name:
Neuronal pentraxin-2, NP2, Neuronal pentraxin II, NP-II
Application Dilution: WB : 1:500 - 1:2000
Specificity: NPTX2 polyclonal antibody detects endogenous levels of NPTX2 protein.
Immunogen:
Recombinant protein of human NPTX2
MW: Predicted band size: 47 kDa, Observed band size: Refer to Figures
Swis Prot.: P47972
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
Alternative Name:
Neuronal pentraxin-2, NP2, Neuronal pentraxin II, NP-II
Application Dilution: WB : 1:500 - 1:2000
Specificity: NPTX2 polyclonal antibody detects endogenous levels of NPTX2 protein.
Immunogen:
Recombinant protein of human NPTX2
MW: Predicted band size: 47 kDa, Observed band size: Refer to Figures
Swis Prot.: P47972
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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