NPY Polyclonal Antibody

NPY Polyclonal Antibody

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In stock
SKU
ELK-ES6406
Catalog Number: ELK-ES6406
Reactivity: Human, Mouse, Rat
Applications: IHC-p, ELISA
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Background:
neuropeptide Y(NPY) Homo sapiens This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014],

Alternative Names:
NPY, Pro-neuropeptide Y

Immunogen: The antiserum was produced against synthesized peptide derived from human NPY. AA range:45-94

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

GeneID: NPY

Storage: -20°C/1 year

NOTE: For Research Use Only
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