NQO1 antibody (clone 1E3-A6), anti-human
€435.00
In stock
SKU
AC-AT3089a
Catalog Number: AC-AT3089a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, IP, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, IP, E
Request Information AC-AT3089a">Request Information
Background:
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Names:
NAD(P)H dehydrogenase [quinone] 1, Azoreductase, DT-diaphorase, DTD, Menadione reductase, NAD(P)H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1, QR1, NQO1, DIA4, NMOR1
Antigen Type:
Recombinant Protein
Gene Name: NQO1 {ECO:0000303|PubMed:1657151, ECO:0000312|HGNC:HGNC:2874}
Gene ID: 1728
NCBI Accession: NP_000894.1;NP_001020604.1;NP_001020605.1
Primary Accession: P15559
Other Accession: BC007659
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Names:
NAD(P)H dehydrogenase [quinone] 1, Azoreductase, DT-diaphorase, DTD, Menadione reductase, NAD(P)H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1, QR1, NQO1, DIA4, NMOR1
Antigen Type:
Recombinant Protein
Gene Name: NQO1 {ECO:0000303|PubMed:1657151, ECO:0000312|HGNC:HGNC:2874}
Gene ID: 1728
NCBI Accession: NP_000894.1;NP_001020604.1;NP_001020605.1
Primary Accession: P15559
Other Accession: BC007659
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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