NQO1 polyclonal (Center), anti-human

NQO1 polyclonal (Center), anti-human

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In stock
SKU
AC-AP7350C
Catalog Number: AC-AP7350C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19087
Applications: IF, FC, WB
Datasheet

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Background:
NQO1 is a member of the NAD(P)H dehydrogenase(quinone) family and a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Altered expression of the protein has been seen in many tumors and is also associated with Alzheimer's disease (AD).

Other Names:
NAD(P)H dehydrogenase [quinone] 1, Azoreductase, DT-diaphorase, DTD, Menadione reductase, NAD(P)H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1, QR1, NQO1, DIA4, NMOR1

Target/Specificity:
This NQO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-144 amino acids from the Central region of human NQO1.

Antigen Region:
118-144

Antigen Type: Synthetic Peptide

Gene Name: NQO1 {ECO:0000303|PubMed:1657151, ECO:0000312|HGNC:HGNC:2874}
Gene ID: 1728
Primary Accession: P15559
NCBI Accession: NP_000894.1;NP_001020604.1;NP_001020605.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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