NQO2 Polyclonal Antibody

Background:
NQO2 (EC 1.10.99.2) is a flavoprotein that catalyzes the 2-electron reduction of various quinones, redox dyes, and the vitamin K menadione. NQO2 predominantly uses dihydronicotinamide riboside (NRH) as the electron donor. The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.

Research Area: Cell Biology, Metabolism, Signal Transduction

Synonyms:
DHQV, DIA6, EC 1.10.99.2, MGC94180, NAD(P)H dehydrogenase quinone 2, NAD(P)H menadione oxidoreductase 1 dioxin inducible 2, NAD(P)H menadione oxidoreductase 2 dioxin inducible, NMOR2, NQO 2, NQO2, NQO2, NRH dehydrogenase [quinone] 2, NRH dehydrogenase, NRH:quinone oxidoreductase 2, OTTHUMP00000015948, OTTHUMP00000015949, OTTHUMP00000015953, Ox 2, Ox2, QR2, Quinone, Quinone reductase 2, Ribosyldihydronicotinamide dehydrogenase [quinone], Ribosyldihydronicotinamide dehydrogenase

Immunogen: Fusion protein of human NQO2

Swissprot: P16083
Gene Accession: BC006096

Calculated MW: 26 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.2 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.