NR0B1 Polyclonal Antibody

Background:
This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Neuroscience

Synonyms:
NR0B1, AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1, SRXY2

Immunogen: Recombinant fusion protein of human NR0B1 (NP_000466.2).

Swissprot: P51843
Gene ID: 190

Calculated MW: 43 kDa/51 kDa
Observed MW: 52 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:10-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.