NR1H3 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP9952A
Catalog Number: AC-AP9952A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23158
Applications: WB, IF, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23158
Applications: WB, IF, FC
Datasheet
Request Information
Background:
NR1H3 form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements.
Other Names:
Oxysterols receptor LXR-alpha, Liver X receptor alpha, Nuclear receptor subfamily 1 group H member 3, NR1H3, LXRA
Target/Specificity:
This NR1H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the Central region of human NR1H3.
Antigen Region:
226-253
Antigen Type: Synthetic Peptide
Gene Name: NR1H3
Gene ID: 10062
Primary Accession: Q13133
NCBI Accession: NP_001123573.1;NP_001123574.1;NP_005684.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
NR1H3 form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements.
Other Names:
Oxysterols receptor LXR-alpha, Liver X receptor alpha, Nuclear receptor subfamily 1 group H member 3, NR1H3, LXRA
Target/Specificity:
This NR1H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the Central region of human NR1H3.
Antigen Region:
226-253
Antigen Type: Synthetic Peptide
Gene Name: NR1H3
Gene ID: 10062
Primary Accession: Q13133
NCBI Accession: NP_001123573.1;NP_001123574.1;NP_005684.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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