NR1H4 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS71159
Background:
This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alternative Name:
BAR, FXR, HRR1, HRR-1, RIP14,
Application Dilution: WB: 1:500 - 1:2000
Specificity: NR1H4 polyclonal antibody detects endogenous levels of NR1H4 protein.
Immunogen:
Recombinant protein of human NR1H4.
MW: ~ 56 kDa
Swis Prot.: Q96RI1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alternative Name:
BAR, FXR, HRR1, HRR-1, RIP14,
Application Dilution: WB: 1:500 - 1:2000
Specificity: NR1H4 polyclonal antibody detects endogenous levels of NR1H4 protein.
Immunogen:
Recombinant protein of human NR1H4.
MW: ~ 56 kDa
Swis Prot.: Q96RI1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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