NR1H4 Polyclonal Antibody

Background:
This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described.

Research Area: Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms:
NR1H4, BAR, FXR, HRR-1, HRR1, PFIC5, RIP14

Immunogen: Recombinant fusion protein of human NR1H4 (NP_001193908.1).

Swissprot: Q96RI1
Gene ID: 9971

Calculated MW: 48 kDa/54 kDa/55 kDa
Observed MW: 59 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.