NR2B polyclonal, anti-human, mouse, rat

Protein Family: Receptors and Channels

Pathway and Disease: Immune System, Nervous and Sensory Systems, Neurodegenerative Disorders, Signaling Molecules and Interaction

Description:
Glutamate [NMDA] receptor subunit epsilon-2 (N-methyl D-aspartate receptor subtype 2B receptor or NR2B) is a NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. NR2B forms heteromeric channel of a zeta subunit, a epsilon subunit (GRIN2A , GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). NR2B i sprimarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells.

Alternate Names: Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NMDAR2B, NR2B, N-methyl-D-aspartate receptor subunit 3, hNR3, NR3, GRIN2B

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: Q13224

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NR2B.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
Xie W et al. 2012. Research Article. Plos ONE. 7(9):e45575. PMID# 23029109.