NR3C1 antibody (clone 2C8), anti-human
€435.00
In stock
SKU
AC-AT3105a
Catalog Number: AC-AT3105a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
Request Information AC-AT3105a">Request Information
Background:
The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined.
Other Names:
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1, NR3C1, GRL
Antigen Type:
Recombinant Protein
Gene Name: NR3C1 (HGNC:7978)
Gene ID: 2908
NCBI Accession: NP_000167.1;NP_001018084.1;NP_001018085.1;NP_001018086.1;NP_001018087.1;NP_001018661.1;NP_001019265.1;NP_001191187.1;NP_001191188.1;NP_001191189.1;NP_001191190.1;NP_001191191.1;NP_001191192.1;NP_00119
Primary Accession: P04150
Other Accession: BC015610
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined.
Other Names:
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1, NR3C1, GRL
Antigen Type:
Recombinant Protein
Gene Name: NR3C1 (HGNC:7978)
Gene ID: 2908
NCBI Accession: NP_000167.1;NP_001018084.1;NP_001018085.1;NP_001018086.1;NP_001018087.1;NP_001018661.1;NP_001019265.1;NP_001191187.1;NP_001191188.1;NP_001191189.1;NP_001191190.1;NP_001191191.1;NP_001191192.1;NP_00119
Primary Accession: P04150
Other Accession: BC015610
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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