NR3C1 Blocking Peptide (C-term)
€363.00
In stock
SKU
AC-BP19840b
Background:
The protein encoded by this gene is a receptor forglucocorticoids that can act as both a transcription factor and asa regulator of other transcription factors. This protein can alsobe found in heteromeric cytoplasmic complexes along with heat shockfactors and immunophilins. The protein is typically found in thecytoplasm until it binds a ligand, which induces transport into thenucleus. Mutations in this gene are a cause of glucocorticoidresistance, or cortisol, resistance. Alternate splicing, the use ofat least three different promoters, and alternate translationinitiation sites result in several transcript variants encoding thesame protein or different isoforms, but the full-length nature ofsome variants has not been determined.
Other Names:
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1, NR3C1, GRL
Target/Specificity:
The synthetic peptide sequence is selected from aa 575-588 of HUMAN NR3C1
Gene Name: NR3C1 (HGNC:7978)
Gene ID: 2908
Primary Accession: P04150
Other Accession: P59667; Q9N1U3; P06537; NP_000167.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a receptor forglucocorticoids that can act as both a transcription factor and asa regulator of other transcription factors. This protein can alsobe found in heteromeric cytoplasmic complexes along with heat shockfactors and immunophilins. The protein is typically found in thecytoplasm until it binds a ligand, which induces transport into thenucleus. Mutations in this gene are a cause of glucocorticoidresistance, or cortisol, resistance. Alternate splicing, the use ofat least three different promoters, and alternate translationinitiation sites result in several transcript variants encoding thesame protein or different isoforms, but the full-length nature ofsome variants has not been determined.
Other Names:
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1, NR3C1, GRL
Target/Specificity:
The synthetic peptide sequence is selected from aa 575-588 of HUMAN NR3C1
Gene Name: NR3C1 (HGNC:7978)
Gene ID: 2908
Primary Accession: P04150
Other Accession: P59667; Q9N1U3; P06537; NP_000167.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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