NR3C1 polyclonal (C-term), anti-human

NR3C1 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP4867b
Catalog Number: AC-AP4867b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB26107
Applications: IF, IHC-P, WB
Datasheet

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Background:
NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance.

Other Names:
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1, NR3C1, GRL

Target/Specificity:
This NR3C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 713-742 amino acids from the C-terminal region of human NR3C1.

Antigen Region:
713-742

Antigen Type: Synthetic Peptide

Gene Name: NR3C1 (HGNC:7978)
Gene ID: 2908
Primary Accession: P04150
NCBI Accession: NP_000167.1;NP_001018084.1;NP_001018085.1;NP_001018086.1;NP_001018087.1;NP_001018661.1;NP_001019265.1;NP_001191187.1;NP_001191188.1;NP_001191189.1;NP_001191190.1;NP_001191191.1;NP_001191192.1;NP_00119
Other Accession: P04150-2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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